A pandemic that originated from a pharmaceutical company's research institute. The infected person becomes a captive of sexual desire and attacks the opposite sex, and the attacked partner is also infected. It has been several years since the incident at the pharmaceutical company where the estrus virus started, and it was forgotten by people in the world. Middle-aged PE teacher Tahara is asked to be by a mysterious man. He wants three women to sleep from a man using the power of the virus ... And to administer the passed estrus virus to them using the position of a teacher. However, Tahara's desire is not limited to that, and it infects the entire school with the virus. All students are infected, and students and teachers rush into orgy with libido everywhere in the school building. Tahara trains infected female students with her own thick meat stick ...